Sorry for jumping in this one a little late ...
Good points all around. I don't know of any multiple component resins that are FDA approved. Some may be, as someone mentioned, compliant based on the raw materials used in the system that are part of an approved list of raw materials the FDA has approved for specific applications. Some are for repeated contact with food such as "21 CFR 177.2600 - Rubber articles intended for repeated use" and others are only suited for contact with dry food, etc, etc.
The issue that becomes very relevant with unmixed materials is the chemical reaction. Even though the raw materials used in a system could be "compliant" on the approved list of raw materials, once those chemicals react they may form a different material which could or could not be safe for the intended use. The other factor is stoichiometry or the "mix". What if the material completely crosslinks at 1:1. Meaning all of the x's find all the o's and nothing is leftover once the material has fully cured. However, say the user dumps their A side cup into their B side cup and the actual ratio used is then 100 parts B to only 95 parts A due to the residue left in the measuring cup. Theoretically the material could be so sensitive to the crosslinking that it is possible you may have all the x's tied up and some remaining o's floating around not crosslinked. Then when tested for ppm of extraction, the material may fail the FDA testing due to the left over uncrosslinked material found in the finished part.
It is my understanding (I am not an FDA expert and don't pretend to be and if you are looking for an expert's ruling on this, please ask one), that the finished product itself would actually have to be tested to be labeled "FDA approved". I do know some extruded plastics are compliant for the use of contact with food. Same goes with many platinum based (or addition cured) silicone rubber systems. The raw materials used in those systems are all listed on the FDA's approved raw material list. However this does not make the rubber FDA Approved. The terminology is typically Compliant once the material is cured and cleaned properly before using. If you needed an item to be FDA approved, you would probably need to spend the necessary money to have the finished product tested and signed off on.
I think the best approach to handling any chemical is as Brian stated, treat them all as hazardous and take whatever precautions possible to protect yourself to unnecessary known and unknown risks to the best of your ability. Don't work in confined spaces, make sure there is adequate ventilation, avoid contact with the materials themselves, know the products you are working with and the hazards associated with them whether you are cleaning the shower or casting a pen blank.
From Alumilite's standpoint, we don't recommend our resins to be used for questionable applications where food contact, pregnancy, children, or even mouth contact is possible due to the potential hazards created from human error and possible unforeseen hazards not known to us or anyone at this time. We simply will not risk the possibility of future issues by simply not recommending our products for questionable applications.
Mike
Alumilite
800 447-9344