From the look of the pens posted to (or linked to) in this thread, I think it's worth experimenting with dyed Cactus Juice before casting. You should be able to get the strands of luffa to suck up dye via the Cactus Juice, then use a contrasting color on the tube and cast in clear resin.
Given how thin the strands of luffa are, you might not even need to put it under vacuum. If so, you can potentially dye different sections of the luffa in different colors to create multicolor/rainbow/etc effects in the luffa in addition to picking up whatever color you want under it via a painted tube…
Dang it, now I need to track down some luffa…already have everything else to try this…