There are a number of manmade materials that have properties similar to glass - acrylic, polyurethane, and polycarbonate for example. Acrylic is often used as a substitute for glass where greater strength (and break resistance) is required. Acrylic and polyurethane are both available as casting materials. Polycarbonate is extremely tough (although not as scratch-resistant), but I don't know if it is available in a form suitable for casting (but then I'm not a casting expert).
Thin acrylic is a bit flexible and can shatter. For example, the plastic cups used by airlines to distribute tepid soft drinks are made of acrylic; they hold up very well (my wife has some she has been reusing daily for years), but can wear out quickly if you squeeze them hard enough. Superglue (cyanoacrylate, or CA) is acrylic, and when glues are compared, CA joints are often described as 'brittle' meaning that a CA joint can fracture if it receives a physical shock, while other glues are described as 'resilient'.
I would think that a final thickness of 1/2" would be pretty strong. But then, I don't know what you mean by 'casual use'.